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Azithromycin Veterinary medicine Azithromycin,CAS no 83905-01-5

CAS NO.83905-01-5

  • FOB Price: USD: 15.00-15.00 /Kilogram Get Latest Price
  • Min.Order: 1 Kilogram
  • Payment Terms: L/C,T/T,
  • Available Specifications:

    99%(1-25)Kilogram

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Product Details

Keywords

  • azithromycin
  • 83905-01-5
  • Veterinary medicine

Quick Details

  • ProName: Azithromycin Veterinary medicine Azith...
  • CasNo: 83905-01-5
  • Molecular Formula: C38H72N2O12
  • Appearance: fine powder
  • Application: Veterinary medicine Azithromycin
  • DeliveryTime: Ship out within 1-3 days after confirm...
  • PackAge: 1kg/bag, 25kg/drum
  • Port: shanghai, guangzhou,beijing,tianjin,qi...
  • ProductionCapacity: 10 Metric Ton/Day
  • Purity: 99%
  • Storage: cool, dry place and avoid strongl ligh...
  • Transportation: DHL,TNT,FEDEX,EMS, by air, by sea
  • LimitNum: 1 Kilogram
  • Related Substances: NMT0.001%
  • Residue on Ignition: <0.1%
  • Heavy Metal: <10ppm
  • Valid Period: 24 months
  • moq: 1kg

Superiority

CAS No.:
83905-01-5
Other Names:
Azithromycin
MF:
C38H72N2O12
EINECS No.:
1806241-263-5
Place of Origin:
Shandong, China (Mainland)
Type:
Antibiotic and Antimicrobial Agents
Grade Standard:
Medicine Grade
Usage:Animal PharmDBaceuticals
Brand Name:    
Model Number:
Azithromycin
Purity:
99%
Molecular Weight:
748.9845
InChI:
InChI=1/C38H72N2O12
Density:
1.18g/cm3
Melting point:
113-115℃
Boiling point:
822.1°C at 760 mmHg
Refractive index:
1.536
Flash point:
451°C
Vapour Pressur:
2.51E-31mmHg at 25°C
Application:
An azalide macrolide antibiotic

Details

Product Description

Description

Azithromycin is an azalide antibiotic, which inhibits the growth of gram negative bacteria, such as Haemophilus influenza.

 

Azithromycin functions by interfering with 50S ribosomal subunit formation and translation, which inhibits the formation of

 

proteins essential for bacterial survival. Studies involving capillary electrophoresis suggest that Azithromycin can be used as a

 

chiral selector for enantiomeric separation of compounds. In addition, Azithrmycin can be used to increase chloride efflux and

 

selectively reduces tumor necrosis factor α in human cystic fibrosis cells. Furthermore, Azithromycin reduces LPS-induced

 

pulmonary neutrophilia in mice, via suppressing the expression of IL-1β.

 

Specification

 

Items Specifications Results
Appearance White or almost white powder White powder
Solubility Practically insoluble in water, freely soluble in anhydrous ethanol and in methylene chloride Conforms
Idetification 1) IR: Conforms to the spectrum of Azithromycin RS Conforms
2) HPLC: The retention time of azithromycin peak in the chromatogram of the assay preparation corresponds to that in the chromatogram of the Standard preparation, as ovtained in the assay
Specific rotation -45°~ -49° -47°
Crystallinity Meets the requirements Conforms
pH 9.0~11.0 (2mg/ml methanol-water(1:1)) 10.1
Water 4.0%~5.0% 4.60%
Residue on ignition ≤0.3% 0.01%
Heavy metals ≤25ppm <25ppm
  Impurity A ≤0.5% Not detected
  Impurity B ≤1.0% 0.40%
  Impurity C ≤0.5% 0.22%
  Impurity J ≤0.3% 0.11%
  Impurity E ≤0.5% Not detected
  Impurity F ≤0.5% <0.10%
  Impurity G ≤0.5% Not detected
Related Substances(HPLC Test 2) Impurity I ≤0.7% Not detected
  Impurity L≤0.5% Not detected
  Impurity M≤0.5% Not detected
  Impurity N ≤0.5% Not detected
  Impurity O≤0.5% 0.11%
  Impurity P ≤0.2% <0.10%
  Any other impuirty ≤0.2% <0.10%
  Total impurities ≤3.0% 0.84%
Residual Solvents Methylene Chlorde≤600ppm Not detected
Acetone ≤5000ppm 330ppm
Assay 945~1030μg/mg (Anhydrous substance ) 978μg/mg
Conclusion The results can conforms with the USP37 standard.