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CAS NO.103-90-2
99%(1-25)Kilogram
paracetamol
| roduct Name: | Acetaminophen |
| Synonyms: | PARACETAMOL BP2001;PARACETAMOL POWDER;PARACETAMOL POWDER BP;PARACETAMOL BP;ACETAMINOPHENOL POWDER PB/USP;PARACETAMOL DC GRADE;PARACETAMOL BP98;PARACETAMOL USP23,BP98 |
| CAS: | 103-90-2 |
| MF: | C8H9NO2 |
| MW: | 151.16 |
| EINECS: | 203-157-5 |
| Product Categories: | Aromatics;Intermediates & Fine Chemicals;PHARMACEUTICALS;Aromatic Phenols;Lipid signaling;DMF file is ok to be provided.;inhibitor;APIs;Pyridines;103-90-2;1 |
| Mol File: | 103-90-2.mol |
| Acetaminophen Chemical Properties |
| Melting point | 168-172 °C(lit.) |
| Boiling point | 273.17°C (rough estimate) |
| density | 1,293 g/cm3 |
| vapor pressure | 0.008Pa at 25℃ |
| refractive index | 1.5810 (rough estimate) |
| Fp | 11 °C |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | ethanol: soluble0.5M, clear, colorless |
| pka | 9.86±0.13(Predicted) |
| form | Crystals or Crystalline Powder |
| color | White |
| PH | 5.5-6.5 (H2O, 20℃)(saturated solution) |
| PH Range | 5.5 - 6.5 (H O, 20 °C) (saturated solution) |
| explosive limit | 15%(V) |
| Water Solubility | 14 g/L (20 ºC) |
| Merck | 14,47 |
| BRN | 2208089 |
| InChIKey | RZVAJINKPMORJF-UHFFFAOYSA-N |
| LogP | 1.098 at 25℃ |
| CAS DataBase Reference | 103-90-2(CAS DataBase Reference) |
| NIST Chemistry Reference | Acetaminophen(103-90-2) |
| IARC | 3 (Vol. 50, 73) 1999 |
| EPA Substance Registry System | Acetaminophen (103-90-2) |
| Safety Information |
| Hazard Codes | Xn,T,F |
| Risk Statements | 22-36/37/38-52/53-36/38-40-39/23/24/25-23/24/25-11 |
| Safety Statements | 26-36-61-37/39-22-45-36/37-16-7 |
| RIDADR | UN 3077 9/PG III |
| WGK Germany | 1 |
| RTECS | AE4200000 |
| Autoignition Temperature | 540 °C |
| TSCA | Yes |
| HazardClass | 9 |
| PackingGroup | III |
| HS Code | 29242930 |
| Hazardous Substances Data | 103-90-2(Hazardous Substances Data) |
| Toxicity | LD50 in mice (mg/kg): 338 orally (Starmer), 500 i.p. (Dahlin, Nelson) |
paracetamol
| Usage and Dosage | Usage This product is antipyretic and analgesic whose international nonproprietary name is Paracetamol. It is the most common non anti-inflammatory analgesia-antipyretic drugs without anti inflammatory and anti rheumatism action. Its antipyretic effect is similar to aspirin, but analgesic effect is weak. It is the best of breed of acetanilid drugs. The product is especially suitable for patients who cannot use carboxylic acids drugs. It is used for cold and toothache. Acetaminophen is also used as organic synthesis intermediates, stabilizer of hydrogen peroxide, photographic chemicals. Dosage 1. Oral (1) Paracetamol tablets or paracetamol capsules: adults take 300～600mg at a time and 3～4 times a day according to the need. The daily dosage should not be greater than 2g. Defervescence treatment is generally less than 3 days and the administration of pain relief lasts less than 10 days. Children take 10～15mg/kg every 4～ 6 hours. The dosage of children under the age of 12 does not exceed 5 times a day, a five-day course at most. This product should not be taken for a long time. 2. Dispersible tablets: When take tablets, disperse them in warm water dispersion. The commonly used amount of children is 10～15mg/kg every 4～ 6 hours. The dosage of children under the age of 12 does not exceed 5 times a day, a five-day course at most. Children under 3 years old cut back on the amount. |
| Application in Particular Diseases | In Osteoarthritis：
|