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CAS NO.357-70-0
99%(1-25)Kilogram98%(1-25)Kilogram
Galanthamine
Galanthamine
Introduction
English name |
Galanthamine |
Latin Name |
Lycoris radiata (L.herit.) |
Other Name |
Lycoris Radiata Extract, Galantamine |
Part Used |
Lycoris Radiata Bulb, Lycoris Radiata Herb |
Active Ingredients |
Galantamine hydrobromide |
Testing Method |
HPLC |
Appearance |
White to offwhite Crystalline powder |
CAS. No |
357-70-0 |
Specification |
99% 98% |
Galanthamine extract is specific, competitive and reversible acetylcholinesterase inhibitor. It is also an allosteric modulator at nicotinic cholinergic receptor sites potentiating cholinergic nicotinic neurotransmission. Both the acetylcholine and nicotine receptors have been suggested as areas related to cognitive impairment. Initially,Galanthamine extract was used in anesthesiology to antagonize the effects of non-depolarizing muscle relaxants, and since then it was rapidly introduced in other areas of medicine, i.e. neurology, ophthalmology, gastroenterology, intensive care and resuscitation, cardiology, physiotherapy.
Galanthamine extract is a product with broad therapeutic index, allowing "soft" manifestation of its effect with individual dosing depending on the particular case.
Several trials already showed that Galantamine 16 and 24 mg/day significantly benefits the cognitive, functional, and behavioral symptoms of AD as compared with placebo and proved also to be very effective in symptomatic treatment of senile dementia of Alzheimer's type.
Function
1.Galanthamine Hydrobromide is the anti-cholinesterase, weak effect.
2.It has strong effect to the central nervous system through the blood brain barrier.
3.It mainly cures the infantile paralysis sequelae, sweeny and myasthenia gravis pseudoparalytica, etc.
4.It also can be applied to puerilism, posttraumatic apoplexy, polyneuritis and radiculitis.Clinic function: mainly used in myasthenia gravis, poliovirus quiescent stage and sequela.
5.It also in polyneuritis, funiculitis and sensorimotor barrier caused by nervous system disease or traumatism.
6,It’s major used in Alzheimer's disease, has the principal function for dement and dysmnesia caused by organic brain damage.
Application
The product is supplied in both a prescription form as well as an over the counter supplement. in twice-a-day tablets, in once-a-day extended-release capsules, and in oral solution. The tablets come in 4 mg, 8 mg, and 12 mg forms. The capsules come in 8 mg, 16 mg, and 24 mg forms.
Galantamine has been used for decades in Eastern Europe and Russia for various indications such as treatment of myasthenia, myopathy, and sensory and motor dysfunction associated with disorders of the central nervous system. In the US, it is FDA approved for the treatment of Alzheimer's disease.